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AstraZeneca and Moderna received the second and third most reports. This may be because it is also the vaccine that's been used most often in the Netherlands. The Pfizer/BioNTech vaccine was most often mentioned in side effect reports. Lareb again stressed that "in the Netherlands, this specific picture has not been reported so far". On Sunday the Dutch government decided to pause the use of the AstraZeneca vaccine after reports of a serious combination of thrombosis and a decreased number of platelets in Denmark and Norway. 4 Some less common side effects include nausea and swollen lymph nodes (especially in the armpit).
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The most common were fatigue, headache, and new or worsened muscle pain. "The reports now give no reason to believe that thrombosis is a side effect of the coronavirus vaccine," Lareb said. In the Pfizer-BioNTech vaccine trials, more than 77 of participants reported at least one systemic reaction. Lareb received "several dozen" reports of coagulation problems such as thrombosis and pulmonary embolism on all coronavirus vaccines.
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"At present, Lareb does not see any patterns of complaints in the reports that indicate serious side effects from which vaccinees may have died." In most of these cases, underlying health problems seem to be the most obvious cause of death. "Almost all had fragile health because of a wide variety of serious underlying health problems and/or advanced age," Lareb said. The center also received 138 reports of people who died in the period after being vaccinated. The most commonly reported side effects were muscle pain, headache, and feeling unwell. By March 14, the Netherlands administered approximately 1.89 million coronavirus vaccines.Īccording to Lareb, most of the reported possible side effects were minor and expected side effects. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. Significant reductions in infection risk were seen starting at 12 days after the first dose, reaching 60% (95% CI 49–68) for ChAdOx1 nCoV-19 and 69% (66–72) for BNT162b2 at 21–44 days and 72% (63–79) for BNT162b2 after 45–59 days.Up to and including March 14, Dutch side effects center Lareb received nearly 11 thousand reports containing 57,391 possible side effects experienced after a coronavirus vaccine. In the Pfizer/BioNTech vaccine trial, the numbers were lower: Severe side effects included fatigue (3.8) and headache (2). 3106 of 103 622 vaccinated individuals and 50 340 of 464 356 unvaccinated controls tested positive for SARS-CoV-2 infection. Local effects were similarly higher in individuals previously infected than in those without known past infection (1♴ times after the first dose of ChAdOx1 nCoV-19 and 1♲ times after the first dose of BNT162b2). Systemic side-effects were more common (1♶ times after the first dose of ChAdOx1 nCoV-19 and 2♹ times after the first dose of BNT162b2) among individuals with previous SARS-CoV-2 infection than among those without known past infection. Local side-effects were reported by 71♹% (150 023 of 208 767) of individuals after the first dose of BNT162b2, by 68♵% (9025 of 13 179) after the second dose of BNT162b2, and by 58♷% (104 282 of 177 655) after the first dose of ChAdOx1 nCoV-19. Systemic side-effects were reported by 13♵% (38 155 of 282 103) of individuals after the first dose of BNT162b2, by 22♰% (6216 of 28 207) after the second dose of BNT162b2, and by 33♷% (116 473 of 345 280) after the first dose of ChAdOx1 nCoV-19. Between Dec 8, and March 10, 2021, 627 383 individuals reported being vaccinated with 655 590 doses: 282 103 received one dose of BNT162b2, of whom 28 207 received a second dose, and 345 280 received one dose of ChAdOx1 nCoV-19.